Walk in today — your health doesn't have to wait.
Expedient, compassionate care for when you need it most. No appointment necessary. We treat non-life-threatening illnesses and injuries with the attention and respect you deserve.
Comprehensive urgent care services for you and your family
Our experienced clinicians are equipped to handle a wide range of acute conditions — from minor fractures to severe allergies — so you can get relief and get back to your life.
Illness & Infection
Flu, strep throat, UTIs, sinus infections, and other common illnesses diagnosed and treated on the same visit.
Injuries & Sprains
Minor fractures, sprains, strains, and soft tissue injuries evaluated and managed promptly in our clinic.
Fast Diagnostics
On-site rapid testing for strep, flu, COVID-19, and urinalysis — results while you wait, not days later.
Wound Care
Cleaning, stitching, and dressing of lacerations and minor wounds with proper aftercare instructions.
Wellness & Prevention
Physicals, vaccinations, and preventive screenings to keep you healthy year-round.
Work & School Physicals
Documentation for employment, sports participation, and school requirements — quick and convenient.
Urgent care, the way it should be
Main Street Urgent Care & Wellness Clinic was founded on a simple conviction: quality healthcare should be accessible, approachable, and immediate — without the wait times and impersonal atmosphere of a traditional emergency room.
Situated along US Highway 278 in the heart of Guin, our clinic serves north-central Alabama with a team dedicated to treating every patient with the same care and attention we would want for our own families. We accept most major insurance plans and offer transparent pricing for self-pay patients.
- Walk-in visits — no appointment needed
- Same-day diagnostics and results
- Most major insurance plans accepted
- Evening and Saturday hours available
- Family-friendly care for all ages
We accept most major insurance plans
Our goal is to make urgent care affordable and straightforward. Call us to confirm your plan, and ask about our self-pay pricing for uninsured patients.
Call (205) 468-3715— A patient from Guin, ALWe were so relieved to find a clinic in Guin that takes the time to explain things and actually listens. The staff made us feel comfortable from the moment we walked in.
Visit us or give us a call
We're located on US Highway 278 in Guin with ample parking. Walk-ins are always welcome during our operating hours.
144 US Highway 278
Guin, AL 35563-2427
Mon – Fri: 8:00 AM – 6:00 PM
Saturday: 9:00 AM – 1:00 PM
Sunday: Closed
